Everything about Methylamine totally explained
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Methylamine is the
chemical compound with a formula of CH
3NH
2. It is a derivative of
ammonia, wherein one H atom is replaced by a
methyl group. It is the simplest primary
amine. It is usually sold as solutions in
methanol (2M),
ethanol (8M),
THF (2M), and
water (40%), or as the
anhydrous gas in pressurized metal containers. It has a strong odour similar to rotten fish. Methylamine is used as a building block for the synthesis of other
organic compounds, including many illicit drugs; in the United States, the
DEA lists methylamine as a precursor, and purchases of any significant quantity are likely to arouse law enforcement attention.
Chemistry
Methylamine is a good
nucleophile as it's highly basic and unhindered. Its use in
organic chemistry is pervasive. For example, it's a precursor to CH
3NCS.
The hydrochloride salt of methylamine, methylammonium chloride, CH
3NH
3Cl, is a colourless powder that can be converted to the amine.
Although methylamine is a gas at room temperature, liquid methylamine can be used as a solvent analogous to
liquid ammonia. It shares some of the properties of liquid ammonia, but is better for dissolving organic substances, in the same way that
methanol is better than
water.
Production
Methylamine is prepared commercially by the reaction of
ammonia with
methanol with
zeolite as catalyst.
» CH
3OH + NH
3 → CH
3NH
2 + H
2O
It can also be readily prepared as the
hydrochloride by the reaction of
hydrochloric acid with
hexamine or by the reaction of
formaldehyde with
ammonium chloride.
» NH
4Cl +
H2CO → CH
2=NH·HCl + H
2O
» CH
2=NH·HCl + H
2CO + H
2O → CH
3NH
2·HCl +
HCOOH
Methylamine serves as a
buffering agent in the
lumen of the
chloroplast in plants, effectively siphoning off protons that are heading for
ATP synthase.
Further Information
Get more info on 'Methylamine'.
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